The Hinck Lab, MCD Biology, UCSC


Cellular Interactions During Organogenesis and Tumorigenesis

Lindsay Hinck, Professor of Molecular, Cell and Developmental Biology

The Hinck lab is interested in understanding how epithelial cells assemble into organs during development, and how the reverse process occurs during cancer when cells disassemble and metastasize to inappropriate locations. Recently, we have been focusing our studies on a family of positional cues, called Slits, which were originally identified in the nervous system where they direct the construction of elaborate networks of neuronal connections. Currently, the laboratory has projects in three areas: building an organ; stem cells and self-renewal; and loss of growth control and cancer.